Description
Product Characteristics: Ccbe1 is required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Synonyms: Polyclonal Ccbe1 antibody, Anti-Ccbe1 antibody, collagen and calcium binding EGF domains 1 antibody, 4933426F18Rik antibody, 9430093N24Rik antibody, KIAA1983 antibody, MGC118667 antibody, mKIAA1983 antibody.
Target Information: This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans. [provided by RefSeq, Mar 2010]